Anyone running MOTS-c and NAD+ combination? What changes have you noticed in energy or recovery?

Ran TRT for years but skipped MOTS-C. Always felt the evidence wasn’t strong enough for me personally.

Respect if someone experiments carefully, but I wouldn’t recommend chasing every new compound that pops up.

I heard about it from a buddy prepping for a hiking trip, not even from the gym crowd…

Honestly I got interested after listening to a few science-heavy podcasts. Whether the real-world payoff justifies the cost… I’m still undecided.

If someone has detailed logs with training, bodyweight, blood glucose, and recovery notes, I’d genuinely love to read them.

Did you stick to the same weekly day? How long before you noticed appetite changes? Also curious if anyone had to reduce their dose because of nausea or other side effects.

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I noticed selegiline made my motivation feel more consistent but I wouldn’t call it a dopamine plug More like slowing the drain

Anyone here running it alongside TRT?

Didn’t do much for my lifts but my morning focus definitely improved.

I tried 2.5mg twice a week for about two months. Biggest thing I noticed was less mental fatigue at work. Gym performance stayed about the same though

Be careful stacking it with a bunch of stimulants.

Does anyone have bloodwork showing any hormone changes from selegiline?

Old school guys have talked about MAO-B inhibitors forever, but people oversell what they actually do.