Janoshik says the sample believed to be 5-Amino-1MQ was tested using two different fentanyl immunoassays, with each test run twice. Even after dilution, all four tests reportedly came back positive.
Does this increase your confidence in the findings, or do you think confirmatory testing (such as LC-MS/MS) is still necessary before drawing conclusions?
Kisspeptin isn’t some unlimited override switch from everything I’ve read.
I feel like people underestimate how complicated hypothalamic signaling really is.
My guess is individual genetics would shift that point all over the place. AR sensitivity isn’t identical from person to person.
There’s also the issue of timing. Pulsatile signaling matters with a lot of these hormones.
Not gonna lie, this sounds more like something for a university lab than a home experiment.
I’ve been on TRT for years and even I wouldn’t try to interpret something this nuanced off symptoms alone.
Years ago everyone blamed estrogen for everything. Now every discussion swings toward DHT. Reality is probably somewhere in between.
I could see two people running identical protocols and ending up with completely different endocrine responses.
