Anyone running MOTS-c and NAD+ combination? What changes have you noticed in energy or recovery?

It’s not just hormones CNS stimulation plays a huge role here.

Elevated androgens seem to mess with REM quality more than total sleep time

I noticed higher resting heart rate at night on cycle definitely impacts sleep depth

People blame one compound but it’s usually the whole stack interacting.

Cortisol rhythm gets thrown off hard with high androgen load

Estrogen imbalance is an underrated factor in sleep disruption

Sleep latency goes up for me even when I’m physically tired

Blood pressure elevation at night is something people ignore

Appetite changes late meals can also disrupt sleep patterns

Breathing feels different almost like mild sleep apnea on bulk cycles

Solid start real fat loss takes time

Good work body changes happen more gradually

Good job early drops include glycogen loss

Great effort long term trends matter most

Encouraging numbers body adapts more gradually