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Retatrutide works upstream on appetite and energy balance clen is downstream brute force
People just see fat loss and assume same category oversimplified thinking
One modulates hormones the other hijacks the sympathetic nervous system
Clen burns fast but comes with systemic stress Retatrutide reshapes metabolism.
Clen relies on beta-adrenergic pathways Retatrutide hits GLP/GIP/glucagon axes
One suppresses appetite heavily the other often increases jitters and sometimes appetite rebound.
Calling them comparable just shows misunderstanding of both compounds