AMPK Activation: MOTS-c vs Fasting vs Exercise?

Guanfacine mainly reduces sympathetic tone no direct pathway to increase height

Height growth is driven by growth plates and hormones not central alpha-2 signaling

Some speculate improved sleep better Growth hormone pulses but that’s indirect

Even if GH secretion improves slightly it doesn’t override genetics or epiphyseal limits

It’s prescribed for ADHD and blood pressure not endocrine growth modulation

Any height gains reported are likely normal growth progression not drug effect.