How effective is PT-141 compared to PDE5 inhibitors (like Viagra) for men?

PT 141 works on the central nervous system brain to increase sexual desire.

PDE5 inhibitors act peripherally by increasing blood flow to the penis

Viagra improves erections PT 141 may improve libido desire more than erections

PT-141 does not rely on nitric oxide mediated vasodilation like PDE5 drugs do

Viagra’s effectiveness for ED is well established with large clinical evidence

PT-141’s research in men is smaller and less definitive than for PDE5 drugs

PT 141 doesn’t require sexual stimulation to potentially affect desire

If ED is due to vascular issues PDE5 drugs are generally more effective

Some men use both classes in combination but safety should be assessed by a clinician

healthcare provider can best assess which option if any aligns with an individual’s symptoms and health status

Effectiveness varies greatly among individuals for both drug classes

PTb141 may affect mood or neural pathways not just genital blood flow