How does pulsatile GH release compare to exogenous GH?

Pulsatile release matches natural physiology and feedback mechanisms.

Exogenous GH creates steady elevated levels lacking pulses.

Natural pulses coordinate better with IGF1 production timing.

Exogenous dosing may suppress endogenous secretion temporarily somewhat.

Pulsatile patterns support balanced metabolic and recovery effects.

Constant exposure may increase desensitization risk over time.

Secretagogues mimic pulsatile release more physiologically accurate overall.

Exogenous GH offers precise control over dosing amounts.

Natural pulsatility reduces shutdown risk compared injections alone.

Both approaches useful depending goals physiology individual response.